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An Update On Transdermal Drug Delivery System (TDDS): A Review
Navneet Kumar Verma, Asheesh Kumar Singh, Sanjay Kumar Srivastava, Ravindra Singh, Sanchit Shukla, Mohd Zubair Sheikh

Transdermal medication administration has become a proven technology in the previous two decades, offering a variety of advantages over the conventional approach. Because transdermal medication delivery allows for regulated and predefined drug distribution into the patient, as well as the ability to easily cease drug action when necessary. Small, lipophilic, low-dose medicines were administered using first-generation transdermal administration. In second-generation transdermal delivery, the medicine was delivered via ultrasound, iontophoresis, and chemical enhancers. Microneedles, electroporation, thermal ablation, and microdermabrasion were employed in third-generation transdermal drug delivery. This review focuses on the numerous modules utilised in medication administration via topical application. The primary goal of a transdermal medication delivery method is to transfer the drug into systemic circulation with minimum inter and intracellular interactions.

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